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The use of medical marijuana continues to be an emotionally and politically charged issue. Though cannabis oil preparations are used in medicine for millennia, the concern over the dangers of misuse resulted in the banning of the medicinal use of marijuana in the 1930s.

Only lately, marijuana and chemically related compounds return to being considered of therapeutic value. A prominent compound found in marijuana or cannabis, CBD, or cannabidiol, has shown to treat a lot of ailments. Researchers believe that in view of the very low toxicity and also the normally benign side effects of CBD, neglecting or denying CBD advantages and its clinical potential is simply unacceptable.

What's CBD?

CBD is just one of over 60 chemicals found in cannabis that belong to a class of ingredients called cannabinoids. Until recently, THC (tetrahydrocannabinol) was getting most of the attention as it is the ingredient in cannabis that produces mind-altering effects in consumers, but CBD can also be present in large concentrations -- and the health care world is realizing that its list of healthcare benefits keeps growing.

CBD is the significant nonpsychoactive part of Cannabis sativa. According to some 2013 study published in the British Journal of Clinical Pharmacology, CBD benefits including acting in certain experimental models as an anti-inflammatory, anticonvulsant, antioxidant, antiemetic, anxiolytic and antipsychotic agent, and it is consequently a possible medicine for treating neuroinflammation, epilepsy, cognitive injury, vomiting and nausea, anxiety and schizophrenia.

Research is beginning to show that CBD is different compared to other well-studied cannabinoids. All cannabinoids act as ligands, meaning they dock on the binding site of a protein and also have the ability to regulate a receptor's behavior. CB1 receptors are widely distributed, but are especially abundant in regions of the mind, such as those concerned with motion, coordination, pain and sensory perception, memory, emotion, cognition, adrenal and adrenal functions.

CB2 receptors are found mostly in the immune system, and they seem to reduce inflammation and certain sorts of pain. Although cannabinoids have similar arrangements, they exhibit a wide array of activities at each of the different receptors.

But, scientists are finding out that CBD has very little effect on CB1 and CB2 receptors, which likely explains why it does not have mind-altering consequences, including THC, which positively regulates the CB1 receptor. That's why most bud grown for recreational purposes are usually quite low in CBD and high in THC.

Proven Benefits of CBD

1. Relieves Pain and Inflammation - Among common CBD benefits, natural pain relief tops the list for many. Evidence suggests that cannabinoids may prove useful in pain modulation by inhibiting neuronal transmission in pain pathways. A 2012 study published in the Journal of Experimental Medicine found the CBD significantly suppressed chronic inflammatory and neuropathic pain in rodents without causing analgesic tolerance. Researchers suggest that CBD and other nonpsychoactive elements of marijuana may represent a novel class of therapeutic agents for treating chronic pain.

2. Has Antipsychotic Effects - Research shows that CBD benefits include producing antipsychotic results. It appears to have a pharmacological profile similar to that of atypical antipsychotic drugs as seen using behavioral and neurochemical techniques in animal research. Furthermore, studies show that CBD averts human experimental psychosis and can be effective in open case reports and clinical trials in patients with schizophrenia, with a remarkable safety profile.

3. Reduces Stress - Studies using animal models of stress and between healthy volunteers certainly indicate an anxiolytic-like effect of CBD. Cannabidiol has shown to decrease anxiety in individuals with social anxiety disorder and researchers suggest it may also be effective for anxiety disorder, obsessive compulsive disorder, social anxiety disorder and post-traumatic anxiety disorder.

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